網頁2024年10月26日 · Dr. Hickson is part of the research team looking at using stem cells to help regenerate failing kidneys. “We take these cells from our abdominal fat and we can … 網頁2024年4月11日 · Background Chemotherapeutic drugs, particularly alkylating cytotoxics such as cyclophosphamide (CTX), play an important role to induce premature ovarian failure (POF). Hormone replacement therapy (HRT) is a widely used treatment to improve hormone secretion. However, the long-term HRT increases the risk of breast cancer and …
Mitochondrial Transfer from Mesenchymal Stem Cells to Macrophages Restricts Inflammation and Alleviates Kidney …
網頁2014年4月1日 · Here, we will review the advances in the kidney regeneration including the manipulation of renal tubular cells, fibroblasts, endothelial cells, and macrophages in renal disease. Several types of stem cells, such as bone marrow-derived cells, adipocyte-derived mesenchymal stem cells, embryonic stem cells, and induced pluripotent stem cells are ... 網頁2024年4月7日 · Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney ... Kadam R, Qadah T, et al. Human Wharton’s jelly stem cell secretions inhibit human leukemic ... production manager metrics
Cellular and Molecular Mechanisms of Kidney Development: From the Embryo to the Kidney Organoid - Frontiers
網頁The Harvard Stem Cell Institute (HSCI) Kidney Group has short, medium, and long-term strategies to develop new therapies for diabetes-related kidney damage (diabetic … 網頁Human kidney tissue can now be generated via the directed differentiation of human pluripotent stem cells. This advance is anticipated to facilitate the modeling of human kidney diseases, provide platforms for nephrotoxicity screening, enable cellular therapy, and potentially generate tissue for renal replacement. All such applications will rely upon the … 網頁2024年4月8日 · Background Kidney stone disease (KSD) is commonly accompanied with renal fibrosis, characterized by accumulation and reorganization of extracellular matrix (ECM). During fibrogenesis, resident renal fibroblasts are activated to become myofibroblasts that actively produce ECM. However, such fibroblast–myofibroblast … production manager onboarding